Laboratories

Labolatory of Cellular Therapy Recruiting students for the academic year 2018

Associate Professor Susumu GOYAMA
+81-3-5449-5782
goyama{at}ims.u-tokyo.ac.jp

Introduction

【Key Words】leukemia, hematological malignancy, hematopoietic stem cells, epigenetics, molecular targeting therapy

Our laboratory is interested in the molecular, cellular, and genetic basis of hematologic malignancies, with a specific focus on Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML). Our research focuses on modeling hematological diseases using both mouse bone marrow transplantation (BMT) and human cell-based Xenograft assays. These models allow us to identify altered genes and signaling pathways, and understand the contribution of these alterations to the pathogenesis of hematologic malignancies. We are currently focusing on two of the most common types of myeloid neoplasms: ASXL1-related and RUNX1-related MDS/AML. We are also investigating factors to enhance the effect of immunotherapy against myeloid tumors. The ultimate goal of our lab is to eventually provide novel therapies to patients with MDS/AML.

Laboratories

The University of Tokyo
Graduate School of Frontier Sciences, The University of Tokyo

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