Laboratory of Stem Cell Dynamics Doesn't recruit students for the academic year 2019

Assosiate Professor Beate HEISSIG
TEL: +81-3-6409-2108
E-mail: heissig{at}
Lab HP


【Key words】stem cell, tissue regeneration, cancer, extracellular matrix, blood vessel formation

 Adult stem cells ensure the maintenance and integrity of tissues/organs and accelerate the repair of damaged tissue by generating tissue-specific cells. We investigate how tissue specific cells, e.g. in the hematopoietic system are regulated under normal and malignant conditions. We are using genetic and cell biological approaches to study the role of proteases in the self-renewal program in hematopoietic stem cells. Since cancer cells seem to copy these selfrenewal mechanisms,we also evaluate the role these mechanisms play in cancer. Aside from the generation of tissuespecific cells,a functional blood vessel network is necessary to improve tissue regeneration and cancer cell growth. Another focus of the lab is to study how proteases modulate blood vessel formation (angiogenesis). Ultimately,it is our mission to identify novel therapeutic targets for diseases like cancer or cardiovascular disorders including peripheral ischemia, myocardial infraction,atherosclerosis and thrombosis.
 For more details regarding our laboratory consisting of researchers and students from around the world, please visit our Web site:


The University of Tokyo
Graduate School of Frontier Sciences, The University of Tokyo

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