Laboratories

Laboratory of Rheumatology Recruiting students for the academic year 2018

Professor Hirotoshi TANAKA
+81-3-5449-5547、+81-3-6409-2405
E-mail:hirotnk{at}ims.u-tokyo.ac.jp
Lab HP

Introduction

【Key Words】Glucocorticoid, Nuclear Receptor, Transcription, Metabolism, Muscle

 Our division is founded in 2013 to tackle systemic autoimmune inflammatory diseases including rheumatoid arthritis, systemic lupus erythematosus and vasculitic syndoromes, and manages increasing number of those in-and outpatients. We provide patients personalized and evidencebased medical service. We participate in cutting edge science of autoimmune, rheumatic and allergic diseases and novel treatments for patients with these disorders. We are interested in the mechanism of eukaryotic gene expression and development of novel therapy and/or drugs that target transcriptional machineries. For this purpose, our recent work is mainly focused on conditional regulation of transcription factors including the glucocorticoid receptor (GR)and inhibitory components of transcription elongation machinery including HEXIM1. Our recent achievement is now being applied in clinical settings in IMSUT Hospital.


Laboratories

The University of Tokyo
Graduate School of Frontier Sciences, The University of Tokyo

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