Laboratories

Division of Stem Cell Pathology Recruiting students for the academic year 2019

Professor Yasuhiro YAMADA
TEL: +81-3-5449-5301
E-mail: yasu{at}ims.u-tokyo.ac.jp
Lab HP

Introduction

【Key Words】 Epigenetics, cancer, iPS cell, ES cell, mouse, developmental genomics


 Epigenetic regulation plays a critical role for the cellular differentiation, the stable maintenance of cellular identity, and the reprogramming process. Accumulating evidence suggests that epigenetic abnormalities represented by abnormal DNA methylation have been involved in various diseases as well. We are interested in unveiling epigenetic regulation in the cellular differentiation, the maintenance of cellular identity, and the pathogenesis including age-related diseases such as cancer. Particularly, taking advantage of reprogramming technology to actively alter epigenetic regulation, we are investigating the role of epigenetic regulation on cancer development, maintenance, and progression. Finally, we will try to develop a novel approach targeting epigenetic regulation to treat cancer patients.

Laboratories

The University of Tokyo
Graduate School of Frontier Sciences, The University of Tokyo

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