Professor Cevayir COBAN
TEL: 03-6409-2219
E-mail: ccoban{at}ims.u-tokyo.ac.jp


【Keywords】Immunopathology, Malaria, Vaccine, Imaging

Although it is eradicated in most countries, malaria, however, is still the disease for poor affecting about 100 countries in the world. There is no successful vaccine available against malaria yet. Why years of scientific research cannot beat Plasmodium parasites (a causative agent of malaria) and eliminate them by vaccines is an important question in my lab. Moreover, while acute malaria kills mostly children, chronic malaria causes unforeseen complications which are not fully understood. We have focused on the host-Plasmodium interactions aiming at understanding how these parasites manipulate the immune system particularly in the context of specific tissue/organs and their specific cell environment (i.e. brain, bone). To achieve our goals we use cutting edge information and technologies. Our overall aim is to use the knowledge derived from state-of-the-art modalities to develop host-mediated therapies to heal acute and chronic complications of malaria and develop new vaccination strategies.

We support our students to access knowledge and provide international environment to enjoy scientific endeavors driven by a scientific curiosity. We believe Plasmodium parasites are challenging tool to study scientific questions related to immunology, parasitology and biology.

Selected publications from the Malaria Immunology Laboratory:

International Immunology, 2020;
Cytometry A, 2019;
European J Immunology, 2019;
Nature Review Immunology, 2018;
Science Immunology, 2017;
Cell Host Microbe, 2014;
Cell Host Microbe, 2012;
Cell Host Microbe, 2010;
Trend. Microbiology, 2007;
J Exp. Medicine, 2005
Coban et al., J Exp. Medicine, 2005